The study of all the metabolites in living organisms and find the correlation between metabolites and physiological and pathological changes is called metabolomics. Since its establishment, metabolomics has developed rapidly and penetrated into many fields, such as disease diagnosis, pharmaceutical research and development, nutritional food science, toxicology, environmental science, botany and other fields closely related to human health care. Stable isotope tracer technique is one of important methods in the metabolism research field. It mainly deduces metabolic pathways and fluxes by analyzing the change rule of stable isotope tracer from precursor to product. The technology makes metabolic studies get great development in above fields, especially in medicine field.

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