Customizing Stable Isotope-labeled Peptides
Customizing Stable Isotope-labeled Peptides
As "chemical labels" in quantitative proteomics, stable isotope-labeled peptides (also known as heavy peptides) are widely used in the detection and tracing of biological samples. The quantitative analysis of proteomics mainly uses high resolution mass spectrometry to separate the isotope labeled and unlabeled peptide ions, and then detected the intensity value of signal to carry out quantitative calculation. The main methods for synthesizing stable isotope-labeled peptides are biosynthesis and chemical synthesis. At Alfa Chemistry, we have produced thousands of high quality peptides for use in proteomics through various methods. And we guarantee superior quality and high isotopic enrichment for the custom synthesis of stable isotope-labeled peptides.
Main Applications
- Functional quantitative proteomics
- Protein expression monitoring
- Allergen detection
- Clinical pathology
- Cell signal analysis and pathway validation
- Protein sequencing
- Drug metabolism
- Drug discovery
- Food safety
- RNA interference
- Pharmacokinetics
- Biomarker discovery
- Pharmacokinetics
Our Services
Over the years of research in stable isotope-labeled compounds, Alfa Chemistry's professional and experienced experts can meet the challenges of most custom synthesis problems. We can provide customized peptides labeled with stable isotopes including 13C (carbon-13), 15N (nitrogen-15), and 2H (deuterium), respectively, or a combination of 15N & 13C. Alfa Chemistry also can design and synthesize high quality stable isotope-labeled peptides according to your needs. Our custom synthesis of stable isotope-labeled peptides has the following characteristics and advantages.
- Adopt highly enriched and quality raw materials and advanced technology.
- The stable isotope-labeled peptides with >99% Isotopic purity.
- The quality control of stable isotope-labeled peptides by liquid chromatography and mass spectrometry.
- Provide various specifications (various solvents, concentration and isotope atoms) upon customer request.
- Concentration accuracy and repeatable result
The following table lists the most common used stable isotope-labeled amino acids in our company that can be used for the custom synthesis of peptides.
| Amino Acid | Isotope | Isotopic Enrichment |
|---|
| Phenylalanine (Phe) | U-13C9, 15N | >99% |
| Alanine (Ala) | U-13C3, 15N | >99% |
| Leucine (Leu) | U-13C6, 15N | >99% |
| Arginine (Arg) | U-13C6, 15N4 | >99% |
| Lysine (Lys) | U-13C6, 15N2 | >99% |
| Valine (Val) | U-13C5, 15N | >99% |
| Proline (Pro) | U-13C5, 15N | >99% |
Ordering Process
Why Choose Us?
- Superior customer service
- Quality assurance
- Provide superior accuracy
- Unparalleled expertise
- Constantly innovating
- Highly skilled teams
- Short detection cycle
- Years of experience
- Competitive price
Please kindly note that our products and services are for research use only.
