Isotope Science / Alfa Chemistry

Radiolabeling and Radiosynthesis

Radioactive labeling and synthesis are a sophisticated technique that combines advanced synthetic chemistry with radioactive isotope application to produce labeled compounds. By introducing radioactive isotopes like carbon-14, tritium, or sulfur-35 into molecules, researchers can track, analyze, and better understand their behavior in complex biological and chemical systems, which are essential for developing new drug, tracing metabolic pathways, determining pharmacokinetics, and studying environmental interactions. Alfa Chemistry provides a wide range of radiolabeling and radiosynthesis services. Over decades of dedicated work in this field, we have refined our methods, built state-of-the-art facilities, and fostered a culture of excellence in radioactive labeling and synthesis. Moreover, our team of experienced radiochemists is committed to efficiently completing every step of the radiolabeling process, ensuring that each project meets the highest standards for quality, safety, and regulatory compliance.

Our Services

We provide a comprehensive suite of radiolabeling and radiosynthesis services, tailored to meet the diverse needs of researchers and developers. Our comprehensive services include:

Carbon-14 Radiosynthesis Services

Alfa Chemistry specializes in synthesizing C-14-labeled compounds of varying complexity, from small molecules to macromolecules.

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Tritium Radiosynthesis Services

Alfa Chemistry specializes in the preparation of a wide range of tritium-labeled compounds for research purposes.

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Sulfur-35 Radiosynthesis Services

Alfa Chemistry specializes in the preparation of sulfur-35 labeled oligonucleotide, nucleotide, proteins, small molecules, etc.

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Synthesis of 14C Radiolabeled API to GMP

Alfa Chemistry specializes in providing high-quality 14C radiolabeled APIs for Phase I, mass balance, and microdosing studies.

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Covalent Radiolabeling of Biomolecules

Alfa Chemistry employs isotopes tritium or carbon-14 to radiolabel large biomolecules for tracking biomolecular behavior.

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For these services, we provide end-to-end support from identifying the optimal labeling site to selecting the best synthetic route and purification method.

  • Design and Optimization: Strategic design of radiolabeling sites and synthetic pathways.
  • Synthesis and Purification: High-purity synthesis, ensuring optimal isotopic incorporation and stability.
  • Analysis and Quality Control: Rigorous testing and certification for compound purity, specific activity, and stability.

Why Partner with Us?

Proven Expertise and Experience: With decades of experience in radiochemistry, we have successfully completed thousands of 14C and 3H synthesis projects.

State-of-the-Art Facilities: Our laboratories are equipped with cutting-edge instrumentation, enabling us to achieve precise radiolabeling and synthesis.

Comprehensive Safety and Compliance: Our processes comply with international regulatory standards, ensuring smooth integration into your research workflows.

End-to-End Project Management: From initial consultation to final delivery, we provide seamless project management to ensure timely and efficient execution.

Custom Solutions for Unique Needs: Our team works closely with each client to understand their unique requirements and tailors solutions accordingly.

Radiolabeling and radiosynthesis are critical tools in advancing scientific knowledge and improving healthcare outcomes. Our service is designed to provide seamless, high-quality support to meet the unique demands of our partners in academia, biotechnology, and pharmaceutical industries. Whether you are conducting preclinical studies, or developing a novel therapeutic, our team is here to support you with customized solutions tailored to your needs. Reach out to us to learn how we can contribute to the success of your next project.

Please kindly note that our products and services are for research use only.
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