Isotope Science / Alfa Chemistry

Sulfur-35 Radiosynthesis Services

Radioisotopes play a pivotal role in drug discovery and development and life science, particularly in understanding pharmacokinetics, metabolism, and target interactions. Sulfur-35 is a widely used radioisotope due to its unique properties, including its relatively long half-life (87.4 days) and ability to label sulfur-containing compounds like peptides, proteins, and small molecules, which offers researchers a unique opportunity to trace and study biological pathways with remarkable clarity. In this respect, synthesis of sulfur-35 labeled compounds is an essential service. At Alfa Chemistry, our specialized sulfur-35 radiosynthesis services provide researchers with tailor-made solutions to meet the needs of sulfur-35 labeled compounds for drug development and various scientific research.

Our Sulfur-35 Radiosynthesis Services

Alfa Chemistry offers a comprehensive suite of sulfur-35 radiosynthesis services, and our specialized synthetic capabilities include the synthesis of sulfur-35 labeled reagents and their subsequent incorporation into a wide range of biomolecules and small molecules, including but not limited to:

  • Sulfur-35 labeled oligonucleotide
  • Sulfur-35 labeled nucleotide
  • Sulfur-35 labeled proteins (Site-specific incorporation of 35S into proteins via cysteine residues or other sulfur-containing amino acids.)
  • Sulfur-35 labeled small molecules (including thiol, thioether, sulfoxide, and sulfone derivatives.)

Key highlights of our services include:

  • Expert advice on the selection and application of sulfur-35 labeled compounds in your studies.
  • Flexible synthesis strategies for diverse sulfur-containing molecules.
  • Rigorous quality assurance to ensure isotopic and chemical purity.
  • Timely delivery to keep your research on schedule.

Comprehensive Analytical Methods and Techniques Support

Accurate characterization and quality control are critical for sulfur-35 labeled compounds. We provide a suite of analytical techniques to ensure the integrity and reliability of synthesized products, and support the fact that we can provide a complete analysis package for each project. Our analytical methods and techniques include, but are not limited to:

  • Radio-TLC and Radio-HPLC: High-resolution techniques for monitoring reaction progress and assessing compound purity.
  • Mass Spectrometry (MS): Verification of molecular structure and isotopic incorporation.
  • Nuclear Magnetic Resonance (NMR): Structural analysis to confirm chemical integrity.
  • Liquid Scintillation Counting (LSC): Precise quantification of radioactivity in samples.
  • Stability Testing: Evaluating the stability of sulfur-35 labeled compounds under various conditions to ensure usability over time.

Why Partner with Us?

Unparalleled Expertise: Our team of radiochemists and synthetic chemists possesses extensive experience in designing and executing complex 35S labeling projects.

Customized Solutions: Our flexible approach allows us to tailor services to your specific goals and challenges.

Advanced Infrastructure: State-of-the-art facilities equipped with cutting-edge instrumentation ensure precise and safe handling of radioactive materials.

Global Delivery: Our robust logistics network allows us to serve clients worldwide, ensuring prompt and reliable delivery of radiolabeled compounds.

Collaborative Approach: We work closely with our clients, offering continuous communication and transparency throughout the synthesis process.

Sulfur-35 compounds and biomolecules provide tools to explore complex biochemical pathways and molecular interactions in pharmaceutical and life sciences. By leveraging advanced techniques, analytical support, and a customer-centric approach, Alfa Chemistry delivers high-quality custom sulfur-35 labeled compounds tailored to your research needs. From initial consultation to delivery of the final product, we are committed to providing exceptional service and support. For additional details about our services or to discuss your requirements, please reach out to us directly.

Please kindly note that our products and services are for research use only.
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