Carbon-14 Radiosynthesis Services

In the realm of radiochemistry, the expertise required to synthesize radiolabeled compounds can be challenging, yet profoundly rewarding. For example, carbon-14 radiosynthesis services provide pivotal contributions to diverse scientific fields such as clinical drug development, metabolic studies, and ecological research. With decades of expertise, Alfa Chemistry's team of highly skilled radiochemistry professionals specializes in synthesizing 14C-labeled compounds of varying complexity, from small molecules to macromolecules. These compounds can support preclinical and clinical studies and drug development, and they also support the fields of environmental fate analysis, skin permeation research, and more. Through meticulous route design and strategic selection of radiolabeling sites, we ensure optimal results tailored to the unique needs of every project.

Why Use Carbon-14 for Radiolabeling?

• Precision and Sensitivity: The radioactive decay of carbon-14 provides a highly sensitive and measurable signal, which can be detected even in small quantities. This allows researchers to accurately measure and track radiolabeled compounds even at low concentrations.
• Long Half-Life: Carbon-14 has a relatively long half-life, making it ideal for long-term studies. This means that the radiolabeled compounds remain detectable over extended periods, which is beneficial in longitudinal studies.
• Non-Invasive Measurement: Many detection methods for carbon-14 (like liquid scintillation counting) are non-invasive and do not require destructive sampling, allowing for continuous monitoring of samples without altering them.
• Chemical Compatibility: As a carbon isotope, carbon-14 seamlessly integrates into organic molecules without altering their chemical behavior.

Our Carbon-14 Radiosynthesis Services

At Alfa Chemistry, we pride ourselves on offering unparalleled expertise in carbon-14 labeling for complex molecules. Our extensive synthesis capabilities allow us to create a wide range of 14C-labeled compounds, covering the needs of various research domains, including:

Comprehensive Analytical Methods and Techniques Support

Our laboratory is equipped with cutting-edge analytical instruments and techniques to support the synthesis, analysis and quality control of radiolabeled compounds, including:

• Vacuum Manifold Equipment: Precise handling of volatile carbon-14 starting materials.
• Preparative Chromatography: Maximizing radiolabeled material recovery with high throughput systems.
• HPLC and LC-MS: High-resolution analysis and characterization of labeled compounds.
• GC-MS: Identification of volatile and semi-volatile radiolabeled materials.
• Radio-TLC Imagers: Efficient imaging for thin-layer chromatography analysis.
• Liquid Scintillation Counting: Quantification of radioactivity in samples.
• NMR and Infrared Spectroscopy: Structural confirmation of synthesized compounds.
• Thermal Analysis: Including DSC and TGA for material characterization.
• KF and ICP-MS Analysis Techniques: Ensure comprehensive quality control and material characterization.
• Bioburden Testing: Ensuring microbial safety of radiolabeled materials.
• Temperature-Controlled Storage: Includes 2-8 °C, -20 °C, and -80 °C facilities, preserving compound integrity.

Our comprehensive analytical suite guarantees the highest level of precision and reliability for every project, and supports the fact that we can provide a complete analysis package for each project.

Why Partner with Us?

With unparalleled expertise and cutting-edge infrastructure, we are committed to synthesizing and delivering high-quality carbon-14 radiolabeled compounds that drive innovation and discovery. Partner with us to unlock the full potential of radiolabeling for your projects. For additional details about our services or to discuss your requirements, please reach out to us directly.

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Carbon-14 Radiosynthesis Services

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