| Catalog Number |
ACMA00049408 |
| Description |
(+/-)-trans-anti-N2-BPDE-dG-15N5 is an isotope labelled analog of (-)-trans-anti-N2-BPDE-dG, which is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair. |
| Synonyms |
[7S-(7alpha,8 β,9 β,10alpha)]-2'-Deoxy-N-(7,8,9,10-tetrahydro-7,8,9-trihydroxybenzo[a]pyren-10-yl)guanosine-15N5; Benzo[a]pyrene, guanosine deriv.-15N5; (+/-)-trans-anti-7,8,9-Trihydroxy-10-(2'-deoxyguanosin-2-yl)benzo[a]pyrene-15N5 |
| IUPAC Name |
9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-[[(7R,8S,9R,10S)-7,8,9-trihydroxy-3,5,7,8,9,10-hexahydrobenzo[a]pyren-10-yl](15N)amino]-1H-purin-6-one |
| Molecular Weight |
576.55 |
| Molecular Formula |
C30H2915N5O7 |
| Canonical SMILES |
C1C=CC2=C3C1=CCC4=CC5=C(C(C(C(C5O)O)O)NC6=NC7=C(C(=O)N6)N=CN7C8CC(C(O8)CO)O)C(=C43)C=C2 |
| InChI |
1S/C30H29N5O7/c36-10-18-17(37)9-19(42-18)35-11-31-24-28(35)33-30(34-29(24)41)32-23-22-15-7-6-13-3-1-2-12-4-5-14(21(15)20(12)13)8-16(22)25(38)27(40)26(23)39/h1,3-4,6-8,11,17-19,23,25-27,36-40H,2,5,9-10H2,(H2,32,33,34,41)/t17-,18+,19+,23-,25+,26+,27-/m0/s1/i31+1,32+1,33+1,34+1,35+1 |
| InChI Key |
CLQHEFGZYOABQI-ONIXWVHMSA-N |
| Storage |
Keep container closed when no tin use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances |
| Type |
Unlabeled Reference Standards |
| Unlabeled CAS |
85026-87-5 |
